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Effects of some transmitters on resting membrane potential of somatic cell in Lumbricus terrestris muscle wall.

Authors
Type
Published Article
Journal
Bulletin of experimental biology and medicine
Publication Date
Volume
136
Issue
2
Pages
189–191
Identifiers
PMID: 14631507
Source
Medline
License
Unknown

Abstract

Serotonin, glutamate, glycine, ATP, and muscarine had no effect on resting membrane potential of muscle cell in earthworm Lumbricus terrestris. Nicotine depolarizes and GABA hyperpolarizes the muscle membrane. Removal of K(+), Cl(-) and addition of ouabaine and strychnine to the solution abolished the effect of GABA. The authors conclude that the Lumbricus terrestris myocyte membrane contains nicotine receptors and GABAergic receptors sensitive to strychnine. Stimulation of these receptors activates sarcolemmal ionic pumps and causes membrane hyperpolarization.

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