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Effects of soman on norepinephrine uptake and electrically stimulated release from human uterine arteries.

Authors
  • Hu, C Y
  • Robinson, C P
Type
Published Article
Journal
Pharmacological research
Publication Date
Jan 01, 1992
Volume
25
Issue
2
Pages
181–185
Identifiers
PMID: 1635895
Source
Medline
License
Unknown

Abstract

The effects of soman on the uptake and electrically induced release of norepinephrine (noradrenaline) from isolated human uterine artery have been investigated. Soman did not alter the uptake of norepinephrine by human uterine artery, but reduced the electrically induced release of norepinephrine from the artery. This reduced norepinephrine release may augment the fall in blood pressure induced by accumulated acetylcholine stimulating muscarinic receptors following cholinesterase inhibition.

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