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The effects of sialic acid on the gene expression of fibrillar collagens: different changes in normal and fibrotic scar derived fibroblasts.

Authors
  • Kössi, J
  • Aalto, J
  • Haataja, S
  • Niinikoski, J
  • Peltonen, J
  • Laato, M
Type
Published Article
Journal
Annales chirurgiae et gynaecologiae. Supplementum
Publication Date
Jan 01, 2001
Issue
215
Pages
25–28
Identifiers
PMID: 12016744
Source
Medline
License
Unknown

Abstract

Sialic acids may decrease collagen gene expression in granulation tissue and that disturbed wound healing in diabetics and smokers may in part be due to direct effect of sialic acids on fibroblasts. Sialic acids may in part induce keloid formation.

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