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Effects of retroviral-mediated tissue plasminogen activator gene transfer and expression on adherence and proliferation of canine endothelial cells seeded onto expanded polytetrafluoroethylene.

Authors
  • Huber, T S1
  • Welling, T H
  • Sarkar, R
  • Messina, L M
  • Stanley, J C
  • 1 Jobst Research Laboratories, Department of Surgery, University of Michigan Medical School, Ann Arbor, USA.
Type
Published Article
Journal
Journal of Vascular Surgery
Publisher
Elsevier
Publication Date
Dec 01, 1995
Volume
22
Issue
6
Pages
795–803
Identifiers
PMID: 8523615
Source
Medline
License
Unknown

Abstract

Lower rates of surface endothelialization by genetically modified ECs in vivo do not appear to be due to an impaired capacity to initially adhere or proliferate on the synthetic graft but may result from decreased adherence after exposure to in vivo hemodynamic forces.

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