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Effects of Retinal Angiography on Optical Coherence Tomography Measurements

Authors
  • Jo, Young-Joon
  • Lim, Hyung-Bin
  • Lee, Soo-Hyun
  • Kim, Jung-Yeul
Type
Published Article
Journal
Ophthalmologica
Publisher
S. Karger AG
Publication Date
May 13, 2015
Volume
234
Issue
3
Pages
160–166
Identifiers
DOI: 10.1159/000381788
PMID: 25998933
Source
Karger
Keywords
License
Green
External links

Abstract

Purpose: To evaluate the effects of retinal angiography, using fluorescein and indocyanine green dyes, on optical coherence tomography (OCT) measurements. Methods: In total, 76 eyes from 76 consecutive patients were included. Macular cube 512 × 128 combination scanning and optic disc 200 × 200 scanning using spectral-domain (SD)-OCT were performed twice, before and after retinal angiography, with fluorescein or indocyanine green. Signal strength, regional retinal thickness of the 9 Early Treatment Diabetic Retinopathy Study subfields, total macular volume, and retinal nerve fiber layer thickness obtained before and after angiography were compared. Repeatability was also investigated. Results: Comparing the results of OCT measured before and after retinal angiography, there was no statistically significant difference in any parameter assessed. The interclass correlation values for each measurement were all >0.808 (range 0.808-0.999). Conclusion: Retinal angiography using fluorescein and indocyanine green dyes has no significant effect on OCT measurements.

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