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Effects of oral antibiotic roxithromycin on quality of life in acne patients.

Authors
  • Kobayashi, Miwa
  • Kabashima, Kenji
  • Nakamura, Motonobu
  • Tokura, Yoshiki
Type
Published Article
Journal
The Journal of dermatology
Publication Date
Jul 01, 2009
Volume
36
Issue
7
Pages
383–391
Identifiers
DOI: 10.1111/j.1346-8138.2009.00664.x
PMID: 19583686
Source
Medline
License
Unknown

Abstract

Macrolides are effective for inflammatory acne, but there are not many studies on roxithromycin. In this study, patients with acne were surveyed for improvement of their quality of life after treatment with roxithromycin. Patients were orally given roxithromycin 300 mg daily for 2-4 weeks. At the time of pre- and post-treatment, the dermatologists graded the severity of acne symptoms, and the patients answered questionnaires. In 123 half faces of 76 patients, 80 half faces were improved, 42 half faces were not changed, and one half face was deteriorated. The score of "symptom and feeling" and "leisure" in DLQI-J and "emotions" and "symptoms" in Skindex-29-J were significantly decreased after roxithromycin treatment. Roxithromycin has a therapeutic effect on inflammatory acne and leads to improvement of quality of life in the patients.

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