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Effects of N-acetylcysteine on microalbuminuria and organ failure in acute severe sepsis: results of a pilot study.

Authors
  • Spapen, Herbert D
  • Diltoer, Marc W
  • Nguyen, Duc N
  • Hendrickx, Inne
  • Huyghens, Luc P
Type
Published Article
Journal
Chest
Publication Date
Apr 01, 2005
Volume
127
Issue
4
Pages
1413–1419
Identifiers
PMID: 15821223
Source
Medline
License
Unknown

Abstract

Early NAC administration does not influence the course of MACR in severe clinical sepsis, suggesting that NAC might not attenuate endothelial damage in this condition. NAC treatment even aggravated sepsis-induced organ failure, in particular cardiovascular failure.

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