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Effects of the melatonin MT-1/MT-2 agonist ramelteon on daytime body temperature and sleep.

Authors
  • Markwald, Rachel R
  • Lee-Chiong, Teofilo L
  • Burke, Tina M
  • Snider, Jesse A
  • Wright, Kenneth P Jr
Type
Published Article
Journal
Sleep
Publication Date
Jun 01, 2010
Volume
33
Issue
6
Pages
825–831
Identifiers
PMID: 20550024
Source
Medline
License
Unknown

Abstract

Ramelteon improved daytime sleep, perhaps mechanistically in part by reducing core temperature and modulating skin temperature. These findings suggest that ramelteon may have promise for the treatment of insomnia associated with circadian misalignment due to circadian sleep disorders.

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