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Effects of Lysine deficiency and Lys-Lys dipeptide on cellular apoptosis and amino acids metabolism.

Authors
  • Yin, Jie1, 2, 3, 4
  • Li, Yuying1, 2, 3, 4
  • Han, Hui1, 2, 3, 4
  • Zheng, Jie5
  • Wang, Lijian1, 2, 3, 4
  • Ren, Wenkai1, 2, 3, 4
  • Chen, Shuai1, 2, 3, 4
  • Wu, Fei1, 2, 3, 4
  • Fang, Rejun5, 6
  • Huang, Xingguo5, 7, 6
  • Li, Chunyong1, 2, 3
  • Tan, Bie1, 2, 3
  • Xiong, Xia1, 2, 3
  • Zhang, Yuzhe1, 2, 3
  • Liu, Gang1, 2, 3
  • Yao, Jiming5, 7
  • Li, Tiejun1, 2, 3, 7, 6, 8
  • Yin, Yulong1, 2, 3, 7, 8
  • 1 Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, Hunan, P. R. China. , (China)
  • 2 Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Changsha, Hunan, P. R. China. , (China)
  • 3 Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Changsha, Hunan, P. R. China. , (China)
  • 4 University of Chinese Academy of Sciences, Beijing, P. R. China. , (China)
  • 5 College of Animal Science and Technology, Hunan Agriculture University, Hunan, P. R. China. , (China)
  • 6 Hunan Co-Innovation Center of Animal Production Safety, Changsha, Hunan, P. R. China. , (China)
  • 7 Guangdong Wangda Group Academician Workstation for Clean Feed Technology Research and Development in Swine, Guangdong Wangda Group Co., Ltd., GuangDong, P. R. China. , (China)
  • 8 National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan, P. R. China. , (China)
Type
Published Article
Journal
Molecular Nutrition & Food Research
Publisher
Wiley (John Wiley & Sons)
Publication Date
Sep 01, 2017
Volume
61
Issue
9
Identifiers
DOI: 10.1002/mnfr.201600754
PMID: 28012236
Source
Medline
Keywords
License
Unknown

Abstract

Altogether, these studies suggest that Lys deficiency impairs AA metabolism and causes apoptosis. Lys-Lys dipeptide serves as a Lys source and alleviates Lys deficiency induced cellular imbalance.

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