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Effects of a low concentration of isoflurane on contrast sensitivity in volunteers.

Authors
  • Taylor, S R
  • Khan, O A
  • Swart, M L
  • Lockwood, G G
  • Jones, J G
Type
Published Article
Journal
British journal of anaesthesia
Publication Date
Aug 01, 1998
Volume
81
Issue
2
Pages
176–179
Identifiers
PMID: 9813518
Source
Medline
License
Unknown

Abstract

The effects of 0.15% quasi steady-state end-tidal isoflurane on the contrast sensitivity of five healthy volunteers were investigated by measuring their performance in computer generated letter discrimination tasks. A series of letters were displayed on a computer screen so that the luminance of the letter differed from that of the background. Two protocols were used: in the static protocol, the letter remained displayed on the screen until the subject responded, whereas in the dynamic protocol, the letter was displayed for 1/72 s only. Isoflurane significantly decreased contrast sensitivity in both protocols in all subjects.

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