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Effects of long-term, once-daily administration of atenolol on ambulatory blood pressure of hypertensive patients.

Authors
  • Floras, J S
  • Jones, J V
  • Fox, P
  • Hassan, M O
  • Turner, K L
  • Sleight, P
Type
Published Article
Journal
Journal of Cardiovascular Pharmacology
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Jan 01, 1981
Volume
3
Issue
5
Pages
958–964
Identifiers
PMID: 6168863
Source
Medline
License
Unknown

Abstract

We measured intraarterial, ambulatory blood pressure over a 24-h period in 12 subjects 24--63 years (mean 47.6) of age with newly diagnosed untreated hypertension. Measurements were performed both before and after 2--9 months of once-daily treatment with atenolol, a cardioselective beta-adrenoceptor antagonist. Significant reductions in arterial pressure (p less than 0.005) during treatment with atenolol (dose range 50--200 mg) were observed over the full 24-h period.

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