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Effects of keratinocyte growth factor in the squamous epithelium of the upper aerodigestive tract of normal and irradiated mice.

Authors
  • Farrell, C L
  • Rex, K L
  • Kaufman, S A
  • Dipalma, C R
  • Chen, J N
  • Scully, S
  • Lacey, D L
Type
Published Article
Journal
International journal of radiation biology
Publication Date
May 01, 1999
Volume
75
Issue
5
Pages
609–620
Identifiers
PMID: 10374943
Source
Medline
License
Unknown

Abstract

These data show that KGF reverses epithelial atrophy in mouse oral cavity caused by irradiation and suggest that KGF may be useful for the treatment of mucositis of the upper aerodigestive tract of patients treated with aggressive regimens of radiation therapy.

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