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Effects of high-dose octreotide LAR on glucose metabolism in patients with acromegaly inadequately controlled by conventional somatostatin analog therapy.

Authors
  • Mazziotti, Gherardo
  • Porcelli, Teresa
  • Bogazzi, Fausto
  • Bugari, Giovanna
  • Cannavò, Salvatore
  • Colao, Annamaria
  • Cozzi, Renato
  • De Marinis, Laura
  • degli Uberti, Ettore
  • Grottoli, Silvia
  • Minuto, Francesco
  • Montini, Marcella
  • Spinello, Maurizio
  • Giustina, Andrea
Type
Published Article
Journal
European Journal of Endocrinology
Publisher
Bioscientifica
Publication Date
Mar 01, 2011
Volume
164
Issue
3
Pages
341–347
Identifiers
DOI: 10.1530/EJE-10-0811
PMID: 21212103
Source
Medline
License
Unknown

Abstract

An increase in octreotide LAR dose or frequency did not impact on glucose metabolism in most patients. Worsening of glucose metabolic status occurred in close relation with persistently uncontrolled acromegaly.

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