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Effects of Cream Containing Ficus carica L. Fruit Extract on Skin Parameters: In vivo Evaluation.

Authors
  • Khan, H
  • Akhtar, N
  • Ali, A
Type
Published Article
Journal
Indian Journal of Pharmaceutical Sciences
Publisher
OMICS Publishing Group
Publication Date
Jan 01, 2014
Volume
76
Issue
6
Pages
560–564
Identifiers
PMID: 25593393
Source
Medline
Keywords
License
Unknown

Abstract

This study was aimed to investigate the effects of cream containing Ficus carica L. fruit (Fig) extract on various skin parameters such as skin melanin, erythema, moisture content, trans-epidermal water loss and sebum. For this purpose, formulation with 4% concentrated extract of F. carica fruit and base without extract were developed. Base served as a control. Both base and formulation were applied to the cheeks of human volunteers for 8 weeks to investigate the effects on different skin parameters using non-invasive bioengineering instruments. Formulation decreased the skin melanin, trans-epidermal water loss and skin sebum significantly. Formulation increased the skin hydration significantly and insignificant effects on skin erythema. We concluded that a stable topical cream (w/o emulsion) containing F. carica fruit extract have effects on skin melanin, trans-epidermal loss, hydration values and sebum content and possibly could be used against for hyper pigmentation, acne, freckles and wrinkle.

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