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Effects of atorvastatin and n-3 fatty acid supplementation on VLDL apolipoprotein C-III kinetics in men with abdominal obesity.

Authors
  • Chan, Dick C
  • Nguyen, Minh N
  • Watts, Gerald F
  • Ooi, Esther Mm
  • Barrett, P Hugh R
Type
Published Article
Journal
American Journal of Clinical Nutrition
Publisher
Oxford University Press
Publication Date
Apr 01, 2010
Volume
91
Issue
4
Pages
900–906
Identifiers
DOI: 10.3945/ajcn.2009.28422
PMID: 20181806
Source
Medline
License
Unknown

Abstract

In obesity, the triglyceride-lowering effect of atorvastatin, but not fish oils, is associated with increased VLDL apo C-III fractional catabolism and hence lower VLDL apo C-III concentrations. Combination treatment provided no significant additional improvement in VLDL apo C-III metabolism compared with atorvastatin alone.

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