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Effects of antihypertensive therapy on cardiac sodium/hydrogen ion exchanger activity and hypertrophy in spontaneously hypertensive rats.

Authors
  • Alvarez, Bernardo V
  • Ennis, Irene L
  • De Hurtado, María C Camilión
  • Cingolani, Horacio E
Type
Published Article
Journal
Canadian Journal of Cardiology
Publisher
Elsevier
Publication Date
Jun 01, 2002
Volume
18
Issue
6
Pages
667–672
Identifiers
PMID: 12107424
Source
Medline
License
Unknown

Abstract

The three treatments regressed cardiac hypertrophy and normalized sodium/hydrogen ion exchange exchange activity in SHR, and losartan was the most effective treatment for reversing cardiac hypertrophy, despite producing effects on blood pressure and sodium/hydrogen exchange activity similar to that of other antihypertensive drugs.

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