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Effects of 36 hour fasting on GH/IGF-I axis and metabolic parameters in patients with simple obesity. Comparison with normal subjects and hypopituitary patients with severe GH deficiency.

Authors
  • Maccario, M
  • Aimaretti, G
  • Grottoli, S
  • Gauna, C
  • Tassone, F
  • Corneli, G
  • Rossetto, R
  • Wu, Z
  • Strasburger, C J
  • Ghigo, E
Type
Published Article
Journal
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity
Publication Date
Aug 01, 2001
Volume
25
Issue
8
Pages
1233–1239
Identifiers
PMID: 11477509
Source
Medline
License
Unknown

Abstract

Short-term fasting does not increase GH secretion in obesity and does not distinguish somatotroph function in obese from that in severe GHD adults. Short-term fasting in obesity has attenuated effects on insulin and IGFBP-1 secretion while it normally increases free fatty acids in spite of any change in GH secretion.

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