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Effectiveness of the Sequential Use of Plastic and Titanium Implants for Experimental Replacement of the Mandibular Defect in Animals Using Preliminary Digital Design

Authors
  • Dolgalev, Al. Al.1
  • Svyatoslavov, D. S.2
  • Pout, V. A.2, 3
  • Reshetov, I. V.2, 3
  • Kastyro, I. V.3, 4
  • 1 Stavropol State Medical University, Ministry of Healthcare of the Russian Federation, Stavropol, Russia , Stavropol (Russia)
  • 2 Sechenov University, Moscow, Russia , Moscow (Russia)
  • 3 Witte Moscow University, Moscow, Russia , Moscow (Russia)
  • 4 Peoples’ Friendship University of Russia (RUDN University), Moscow, Russia , Moscow (Russia)
Type
Published Article
Journal
Doklady Biochemistry and Biophysics
Publisher
Pleiades Publishing
Publication Date
Mar 10, 2021
Volume
496
Issue
1
Pages
36–39
Identifiers
DOI: 10.1134/S160767292101004X
Source
Springer Nature
Keywords
License
Yellow

Abstract

AbstractUsing the templates preliminarily made by 3D design and prototyping methods, defects in the lateral area of the lower jaw of sheep were created using the piezosurgical technique. The defects were replaced by plastic implants obtained by the method of layer-by-layer fusion of the FDM printing–fusing deposition modeling and fixation with titanium screws to the jaw body. In the time interval, plastic implants are replaced by titanium implants obtained by selective laser sintering (SLS) using a 3D printer. To study the processes of reparative osteogenesis, microsamples of tissues of the preimplantation zone were analyzed. As a result, signs of osteo- and fibro-osseointegration were identified. The obtained data are regarded as a prerequisite for further clinical trials of the developed protocols for the sequential replacement of jaw defects using 3D printing.

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