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Effective knock down of very high ABCG2 expression by a hammerhead ribozyme.

Authors
  • Kowalski, Petra
  • Farley, Kate M
  • Lage, Hermann
  • Schneider, Erasmus
Type
Published Article
Journal
Anticancer research
Publication Date
Jan 01, 2004
Volume
24
Issue
4
Pages
2231–2235
Identifiers
PMID: 15330166
Source
Medline
License
Unknown

Abstract

The ribozyme used was highly effective in reducing the expression of its target gene, ABCG2, and was able to modulate the associated multidrug-resistant phenotype.

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