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The effect of tunicamycin on interferon-alpha production in a human lymphoblastoid cell line (Namalwa).

Authors
Type
Published Article
Journal
The Journal of general virology
Publication Date
Volume
63 (Pt 1)
Pages
213–216
Identifiers
PMID: 6816905
Source
Medline

Abstract

Tunicamycin alters the biological properties of human interferon-alpha (HuIFN-alpha) produced in its presence by changing the mixture of IFN-alpha subtypes produced. When IFN mRNA extracted from treated cells was microinjected into oocytes the product was also altered. However, treatment of the oocytes with tunicamycin did not alter the properties of the IFN-alpha produced.

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