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[The effect of Tomesa therapy on epidermal Langerhans cells in experimental animals].

Authors
  • Gruner, S
  • Zwirner, A
  • Diezel, W
  • Boonen, H
  • Sönnichsen, N
Type
Published Article
Journal
Dermatologische Monatschrift
Publication Date
Jan 01, 1990
Volume
176
Issue
7
Pages
399–402
Identifiers
PMID: 2147911
Source
Medline
License
Unknown

Abstract

In the last years a new therapy of psoriasis was developed, which consists in a treatment with salt solutions, resembling the water of the Dead Sea, and ultraviolet light (Tomesa-therapy). We studied the influence of the used salt on ATPase positive epidermal Langerhans cells in murine ear skin. An irreversible partial reduction of the Langerhans cell ATPase was found after salt treatment of separated epidermis or of full skin preparations. These results may have implications for the optimization and broader application of this therapy.

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