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The effect of the sun on expression of beta-catenin, p16 and cyclin d1 proteins in melanocytic lesions.

Authors
  • Demirkan, N C
  • Kesen, Z
  • Akdag, B
  • Larue, L
  • Delmas, V
Type
Published Article
Journal
Clinical and experimental dermatology
Publication Date
Nov 01, 2007
Volume
32
Issue
6
Pages
733–739
Identifiers
PMID: 17868395
Source
Medline
License
Unknown

Abstract

An immunohistochemical panel including melanocytic markers enriched by p16 and cyclin D1 could be used to differentiate some borderline melanocytic lesions. In addition, the Wnt/beta-catenin pathway was more frequently activated in non-CSD than in CSD melanocytic lesions.

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