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Effect of Statin Therapy on Arterial Wall Inflammation Based on 18F-FDG PET/CT: A Systematic Review and Meta-Analysis of Interventional Studies

Authors
  • Pirro, Matteo
  • Simental-Mendía, Luis E.
  • Bianconi, Vanessa
  • Watts, Gerald F.
  • Banach, Maciej
  • Sahebkar, Amirhossein
Publication Date
Jan 18, 2019
Source
MDPI
Keywords
Language
English
License
Green
External links

Abstract

0.069, p = 0.037). Statin dose/duration, plasma cholesterol and C-reactive protein level changes, and baseline TBR did not affect the TBR treatment response to statins. Conclusions. Statins were effective in reducing arterial wall inflammation, as assessed by 18F-FDG PET/CT imaging. Larger clinical trials should clarify whether either cholesterol-lowering or other pleiotropic mechanisms were responsible for this effect.

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