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[Effect of sodium fluoride on bone tissue regeneration in hypodynamia].

Authors
Type
Published Article
Journal
Patologicheskaia fiziologiia i èksperimental'naia terapiia
Publication Date
Issue
2
Pages
58–60
Identifiers
PMID: 1408401
Source
Medline

Abstract

It was demonstrated in rat experiments that a nonsupported position of the extremity attained by exarticulation of the leg in 10 to 40 days leads to a sharp inhibition of posttraumatic regeneration of bone tissue. Daily injection of 0.4 mg/100 g sodium fluoride, which was used in the clinic for the prevention and treatment of osteoporosis, inhibited still more the regenerative processes both under conditions of hypodynamia and also when the supporting function of the extremity was maintained.

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