Affordable Access

[The effect of riboflavin, molybdenum, selenium and zinc on the development of induced tumors of the esophagus and forestomach in rats].

Authors
  • Bespalov, V G
  • Troian, D N
  • Petrov, A S
  • Aleksandrov, V A
Type
Published Article
Journal
Voprosy onkologii
Publication Date
Jan 01, 1990
Volume
36
Issue
5
Pages
559–563
Identifiers
PMID: 2378079
Source
Medline
License
Unknown

Abstract

The study was concerned with the influence of prolonged treatment with riboflavin, molybdenum, selenium and zinc on the induction of tumors of the esophagus and forestomach by N-nitrososarcosine ethyl ester (NSEE) in rats. Riboflavin was fed whereas molybdenum, selenium or zinc were given in drinking water after the discontinuation of treatment with NSEE, once hyperplasia and dysplasia became evident in the mucous membrane of the esophagus and forestomach. Riboflavin and molybdenum decreased the incidence of carcinoma and multiplicity of papilloma of the organs. Selenium and zinc did not affect the carcinogenesis in the organs discussed.

Report this publication

Statistics

Seen <100 times