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Effect of proton pump inhibitors on the detection of Helicobacter pylori in gastric biopsies.

Authors
Type
Published Article
Journal
Alimentary pharmacology & therapeutics
Publication Date
Volume
10
Issue
3
Pages
289–293
Identifiers
PMID: 8791953
Source
Medline

Abstract

Treatment with a proton pump inhibitor before endoscopy reduces the sensitivity of antral and corpus biopsies for H. pylori detection, both by urease testing and histological examination. If proton pump inhibitors already prescribed cannot be discontinued for an adequate period before endoscopy, patients should have biopsies taken from the corpus as well as from the antrum, and serum should be tested for H. pylori.

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