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[Effect of protein metabolism inhibitors on parasympathetic innervation and cholinergic factors in the frog heart].

Authors
Type
Published Article
Journal
Fiziologicheskiĭ zhurnal SSSR imeni I. M. Sechenova
Publication Date
Volume
70
Issue
6
Pages
829–832
Identifiers
PMID: 6479366
Source
Medline
License
Unknown

Abstract

Protein exchange inhibitors levomycetine and cyclophosphane weakened parasympathetic effects. Levomycetine decreased the content (and synthesis) of acetylcholine (Ach) in heart homogenate while causing no changes of cholinesterase (ChE) activity. Cyclophosphane induced both the decrease of Ach content in the heart and the simultaneous reduction of ChE activity.

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