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[Effect of polyanions on macrophage-lymphocyte interaction].

Authors
Type
Published Article
Journal
Zhurnal mikrobiologii, epidemiologii, i immunobiologii
Publication Date
Issue
2
Pages
84–87
Identifiers
PMID: 6166138
Source
Medline
License
Unknown

Abstract

The effect of polyanions on the interaction of antigen-stimulated macrophages and lymphocytes was studied in vivo. Treatment of cell mixture of macrophages and lymphocytes with poly = A : U or dextran sulfate induced a considerable increase in the number of lymphocytes contacting with macrophages during the first hours of cultivation. Under similar conditions yeast RNA had a certain anticooperative effect. According to the data obtained by scanning electron microscopy, the contacts between the interacting cells were realized by means of cytoplasmic bridges or close membrane connections.

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