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Effect of natsudaidain isolated from Citrus plants on TNF-alpha and cyclooxygenase-2 expression in RBL-2H3 cells.

Authors
  • Matsui, Takuya
  • Ito, Chihiro
  • Itoigawa, Masataka
  • Okada, Tadashi
  • Furukawa, Hiroshi
Type
Published Article
Journal
The Journal of pharmacy and pharmacology
Publication Date
Jan 01, 2009
Volume
61
Issue
1
Pages
109–114
Identifiers
DOI: 10.1211/jpp/61.01.0015
PMID: 19126304
Source
Medline
License
Unknown

Abstract

These findings suggest that natsudaidain inhibits tumour necrosis factor-alpha and cyclooxygenase-2 production by suppressing p38 MAPK phosphorylation but not p65 NFkappaB phosphorylation, and that natsudaidain might alleviate inflammatory diseases.

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