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Effect of the Mutual Arrangement of Substituents in an Aminobenzoic Acid Molecule on the Analytical Performance of a Label-Free Electrochemical Immunosensor with a Covalent-Immobilized Receptor Layer

Authors
  • Svalova, T. S.1
  • Zaidullina, R. A.1
  • Malysheva, N. N.1
  • Saraeva, S. Yu.1
  • Matern, A. I.1
  • Kozitsina, A. N.1
  • 1 Institute of Chemical Technology, Ural Federal University, Yekaterinburg, 620002, Russia , Yekaterinburg (Russia)
Type
Published Article
Journal
Journal of Analytical Chemistry
Publisher
Pleiades Publishing
Publication Date
Apr 14, 2021
Volume
76
Issue
4
Pages
503–509
Identifiers
DOI: 10.1134/S106193482102012X
Source
Springer Nature
Keywords
License
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Abstract

AbstractWe studied the effect of the mutual arrangement of substituents in an aminobenzoic acid molecule on the analytical characteristics of the determination of bacteria Staphylococcus aureus using a label-free electrochemical immunosensor. An immunosensor based on m-aminobenzoic acid demonstrated the best performance. This is apparently due to the best combination of the density of the coating formed by electrochemical deposition and the availability of carboxyl functional groups for carbodiimide cross-linking with an immunoreceptor.

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