Affordable Access

deepdyve-link
Publisher Website

Effect of monthly high-dose vitamin D on bone density in community-dwelling older adults substudy of a randomized controlled trial.

Authors
  • Reid, I R1, 2
  • Horne, A M1
  • Mihov, B1
  • Gamble, G D1
  • Al-Abuwsi, F1
  • Singh, M1
  • Taylor, L1
  • Fenwick, S1
  • Camargo, C A3
  • Stewart, A W4
  • Scragg, R4
  • 1 Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand. , (New Zealand)
  • 2 Department of Endocrinology, Auckland District Health Board, Auckland, New Zealand. , (New Zealand)
  • 3 Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • 4 School of Population Health, University of Auckland, Auckland, New Zealand. , (New Zealand)
Type
Published Article
Journal
Journal of internal medicine
Publication Date
Nov 01, 2017
Volume
282
Issue
5
Pages
452–460
Identifiers
DOI: 10.1111/joim.12651
PMID: 28692172
Source
Medline
Keywords
License
Unknown

Abstract

This substudy finds no clinically important benefit to BMD from untargeted vitamin D supplementation of older, community-dwelling adults. Exploratory analyses suggest meaningful benefit in those with baseline 25-hydroxyvitamin D ≤ 30 nmol L-1 . This represents a significant step towards a trial-based definition of vitamin D deficiency for bone health in older adults.

Report this publication

Statistics

Seen <100 times