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[Effect of the mitochondrial ionophore for divalent cations on bilayer phospholipid membranes].

Authors
Type
Published Article
Journal
Biofizika
Publication Date
Volume
20
Issue
2
Pages
225–227
Identifiers
PMID: 1170900
Source
Medline

Abstract

It has been shown that ionophore of bivalent cations (IBC) isolated from fatless, subjected to partial triptic hydrolysis cattle heart or liver mitochondria decreases BPM resistance inducing Ca2+ conductivity. Ions of lanthane in micromolar concentrations decrease calcium conductivity induced with IBC. When ten-fold gradient in Ca2+ was created on BPM the intitiation of the membrane potential fo 9-11 mV was observed. The role fo IBC and water soluble factors binding Ca2+ with high affinity, in the mitochrondial mechanism of Ca2+ translocation is discussed.

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