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Effect of maturation on the sensitivity of laryngeal resistance to chemoreceptor stimulation in the dog.

Authors
  • Blum, D J
  • McCaffrey, T V
Type
Published Article
Journal
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
Publication Date
Jun 01, 1985
Volume
93
Issue
3
Pages
351–354
Identifiers
PMID: 3927229
Source
Medline
License
Unknown

Abstract

The respiratory system undergoes many changes with maturation, resulting in increased capacity and efficiency. In an effort to determine the effects of maturation on airway control, laryngeal airway resistance was studied from infancy to adulthood in dogs. Reflex regulation of laryngeal airway resistance in response to chemoreceptor stimulation was found in puppies 1 day of age and older. Chemoreceptor-mediated laryngeal reflexes were qualitatively similar in all age groups. However, a significant quantitative difference was found. With maturation, an increase in the sensitivity of both central and peripheral chemoreceptors regulating laryngeal resistance is realized.

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