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Effect of low intravaginal doses of prostaglandin E2 on the closure time of the ductus arteriosus in term newborn infants.

Authors
  • Danford, D A
  • Rayburn, W F
  • Miller, A M
  • Felix, G L
  • Bussey, M E
Type
Published Article
Journal
The Journal of Pediatrics
Publisher
Elsevier
Publication Date
Apr 01, 1993
Volume
122
Issue
4
Pages
632–634
Identifiers
PMID: 8463916
Source
Medline
License
Unknown

Abstract

Seventeen term newborn infants (control subjects) and 17 whose mothers had been given intravaginal doses of prostaglandin E2 (PGE2) were examined serially by color Doppler echocardiography to determine whether maternal PGE2 prolonged ductal patency. No clinically relevant differences in closure times were found. Low-dose intravaginal PGE2 therapy was not associated with prolonged ductal patency in term infants.

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