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Effect of lipid-lowering strategies on tubular cell biology.

Authors
  • Vrtovsnik, F
  • Essig, M
  • Iimura, O
  • Friedlander, G
Type
Published Article
Journal
Kidney international. Supplement
Publication Date
Jul 01, 1999
Volume
71
Identifiers
PMID: 10412747
Source
Medline
License
Unknown

Abstract

HMG-CoA reductase inhibitors decreased proliferation, increased apoptosis, and enhanced fibrinolytic activity of renal tubular cells via modulation of different isoprenylated proteins. These effects could participate to reduce the progression of renal diseases.

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