[Effect of let-7c on the proliferation of human hepatocellular carcinoma cell HCCLM3].
- Authors
- Type
- Published Article
- Journal
- Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology
- Publication Date
- Nov 01, 2011
- Volume
- 19
- Issue
- 11
- Pages
- 853–856
- Identifiers
- DOI: 10.3760/cma.j.issn.1007-3418.2011.11.014
- PMID: 22433309
- Source
- Medline
- License
- Unknown
Abstract
Let-7c can inhibit proliferation of HCCLM3 cells and increase the proportion of cells in G1 phase. The mechanism may be that let-7c represses the expressions of cyclin D1 at both protein and mRNA levels.
