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[Effect of let-7c on the proliferation of human hepatocellular carcinoma cell HCCLM3].

Authors
  • Gong, Fang-xiao
  • Xia, Jing-lin
  • Yang, Bi-wei
  • Xu, Xiao-jing
  • Wu, Wei-zhong
Type
Published Article
Journal
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology
Publication Date
Nov 01, 2011
Volume
19
Issue
11
Pages
853–856
Identifiers
DOI: 10.3760/cma.j.issn.1007-3418.2011.11.014
PMID: 22433309
Source
Medline
License
Unknown

Abstract

Let-7c can inhibit proliferation of HCCLM3 cells and increase the proportion of cells in G1 phase. The mechanism may be that let-7c represses the expressions of cyclin D1 at both protein and mRNA levels.

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