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Effect of lecithin-bound iodine on the patients with bronchial asthma.

Authors
  • Kawano, Yutaka
  • Saeki, Toshiaki
  • Noma, Takeshi
Type
Published Article
Journal
International Immunopharmacology
Publisher
Elsevier
Publication Date
Apr 01, 2005
Volume
5
Issue
4
Pages
805–810
Identifiers
PMID: 15710348
Source
Medline
License
Unknown

Abstract

Lecithin-bound iodine (LBI), which has been reported to be a potential candidate for one of the therapeutic modalities for children with bronchial asthma based on the in-vitro study, was also found to be effective in relieving the symptoms of patients with childhood asthma. In addition to the in-vitro effect of downregulation and upregulation of interleukin-4 (IL-4) and interferon-gamma (IFN-gamma), respectively, the clinical effect of LBI was highlighted through the concomitant upregulation of IFN-gamma production by the patients' lymphocytes, which were treated with LBI for 8 weeks. Therefore, LBI may reduce the signs of bronchial asthma by upregulating the synthesis of IFN-gamma that is a representative Th1 cytokine.

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