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Effect of lactulose on establishment of a rat non-alcoholic steatohepatitis model.

Authors
  • Fan, Jian-Gao
  • Xu, Zheng-Jie
  • Wang, Guo-Liang
Type
Published Article
Journal
World Journal of Gastroenterology
Publisher
Baishideng Publishing Group Co
Publication Date
Aug 28, 2005
Volume
11
Issue
32
Pages
5053–5056
Identifiers
PMID: 16124065
Source
Medline
License
Unknown

Abstract

Lactulose could ameliorate the hepatic inflammation of rats with steatohepatitis induced by fat-rich diet, but could not completely prevent the development of steatohepatitis. It is suggested that intestinal environmental changes such as intestinal bacteria overgrowth, are one of the important factors in the pathogenesis of NASH.

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