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Effect of Lactobacillus reuteri on the prevention of hypercholesterolemia in mice.

Authors
  • Taranto, M P
  • Medici, M
  • Perdigon, G
  • Ruiz Holgado, A P
  • Valdez, G F
Type
Published Article
Journal
Journal of dairy science
Publication Date
Mar 01, 2000
Volume
83
Issue
3
Pages
401–403
Identifiers
PMID: 10750094
Source
Medline
License
Unknown

Abstract

Administration of Lactobacillus reuteri CRL 1098 (10(4) cells/d) to mice for 7 d before inducing hypercholesterolemia (by feeding mice with a fat-enriched diet for the subsequent 7 d) was evaluated. At this low dose, L. reuteri was effective in preventing hypercholesterolemia in mice, producing a 17% increase in the ratio of high-density lipoprotein to low-density lipoprotein. Total cholesterol and triglycerides decreased by 22 and 33%, respectively, in the group that was not fed the lactobacilli. The hypocholesterolemic effect produced by L. reuteri CRL 1098 might be considered as indirect evidence of the permanency of the lactobacilli in the gut.

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