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Effect of intravenous human gastrin-releasing peptide on food intake in humans.

Authors
  • Gutzwiller, J P
  • Drewe, J
  • Hildebrand, P
  • Rossi, L
  • Lauper, J Z
  • Beglinger, C
Type
Published Article
Journal
Gastroenterology
Publisher
Elsevier
Publication Date
May 01, 1994
Volume
106
Issue
5
Pages
1168–1173
Identifiers
PMID: 8174879
Source
Medline
License
Unknown

Abstract

This study shows that intravenous infusions of GRP can decrease spontaneous food intake at concentrations that produce physiological effects, such as stimulation of acid or pancreatic secretion or gallbladder contraction. The data imply that GRP-like peptides can act as satiety signals in humans, confirming data previously reported in animals.

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