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Effect of imipramine and ect on platelet mao activity in depressives.

Authors
Type
Published Article
Journal
Indian Journal of Psychiatry
0019-5545
Publisher
Medknow Publications
Publication Date
Volume
31
Issue
2
Pages
139–143
Identifiers
PMID: 21927372
Source
Medline

Abstract

Platelet monoamine Oxidase (MAO) activity was estimated in 30 depressed patients treated with Imipramine or EGT over a period of 5 weeks and pretreatment and post treatment values were compared. Imipramine and ECT caused significant reduction of platelet MAO, which after 7 days washout period comes to the pretreatment level while subjects clinical status l remained unchanged. The percentage blockade in platelet MAO values by Imipramine and ECT was 51.40±13.43 and 34.73±24.27 respectively.

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