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The effect of IgG levels on the number of natural killer cells and their Fc receptors in chronic inflammatory demyelinating polyradiculoneuropathy.

Authors
  • Bohn, A B
  • Nederby, L
  • Harbo, T
  • Skovbo, A
  • Vorup-Jensen, T
  • Krog, J
  • Jakobsen, J
  • Hokland, M E
Type
Published Article
Journal
European journal of neurology
Publication Date
Jun 01, 2011
Volume
18
Issue
6
Pages
919–924
Identifiers
DOI: 10.1111/j.1468-1331.2010.03333.x
PMID: 21219545
Source
Medline
License
Unknown

Abstract

The study implies that IVIg infusion induces a substantial decline in the number of peripheral NK cells and a suppression of NK-cell-mediated cytotoxicity. We propose that these impairments of the NK cells contribute to the therapeutic effect of IVIg in CIDP.

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