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The effect of hormone replacement therapy and tibolone on lipoprotein (a) concentrations in postmenopausal women: A systematic review and meta-analysis.

Authors
  • Anagnostis, Panagiotis1
  • Galanis, Petros2
  • Chatzistergiou, Vasileia3
  • Stevenson, John C4
  • Godsland, Ian F5
  • Lambrinoudaki, Irene6
  • Theodorou, Mamas7
  • Goulis, Dimitrios G3
  • 1 Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Greece. Electronic address: [email protected]
  • 2 Center for Health Services Management and Evaluation, Department of Nursing, National and Kapodistrian University of Athens, Greece.
  • 3 Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Greece.
  • 4 National Heart and Lung Institute, Imperial College London, Royal Brompton and Harefield NHS Foundation Trust, London SW3 6NP, UK.
  • 5 Diabetes Endocrinology and Metabolic Medicine, Faculty of Medicine, Imperial College London,St. Mary's Campus, London, UK.
  • 6 Second Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens, Greece.
  • 7 Health Policy and Management Department, Open University of Cyprus, Cyprus.
Type
Published Article
Journal
Maturitas
Publication Date
May 2017
Volume
99
Pages
27–36
Identifiers
DOI: 10.1016/j.maturitas.2017.02.009
PMID: 28364865
Source
Medline
Keywords
License
Unknown

Abstract

HRT significantly decreases Lp(a) concentrations, with oral being more effective than transdermal estradiol. The type of HRT, dose of estrogen and addition of progestogen do not seem to modify the Lp(a)-lowering effect of HRT.

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