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Effect of Gravitational Gradients on Cardiac Filling and Performance.

Authors
  • Negishi, Kazuaki1
  • Borowski, Allen G2
  • Popović, Zoran B2
  • Greenberg, Neil L2
  • Martin, David S3
  • Bungo, Michael W4
  • Levine, Benjamin D5
  • Thomas, James D6
  • 1 Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio; Menzies Research Institute Tasmania, Hobart, Australia. , (Australia)
  • 2 Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio.
  • 3 Wyle Science, Technology, and Engineering, Cardiovascular Laboratory at the National Aeronautics and Space Administration Johnson Space Center, Houston, Texas.
  • 4 University of Texas Medical School, Houston, Texas.
  • 5 the Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas and the University of Texas Southwestern Medical Center, Dallas, Texas.
  • 6 Bluhm Cardiovascular Institute, Northwestern University, Chicago, Illinois. Electronic address: [email protected]
Type
Published Article
Journal
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
Publication Date
Oct 19, 2017
Identifiers
DOI: 10.1016/j.echo.2017.08.005
PMID: 29056408
Source
Medline
Keywords
License
Unknown

Abstract

Preload modification with gravitational loading alters most hemodynamic and echocardiographic parameters including e' velocity, GLS, and GCS. However, end-systolic elastance and strain rate appear to be more load-independent measures to examine alterations in the cardiovascular function during postural and preload changes, including microgravity.

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