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[Effect of glycyrrhetinic acid on invasive capacity of leukemic cells and activity of gelatinase].

Authors
  • Zhang, Jin-Ling1
  • Liu, Xin-Yue
  • Zou, Ping
  • 1 Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan.
Type
Published Article
Journal
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
Publication Date
Oct 01, 2008
Volume
28
Issue
10
Pages
903–906
Identifiers
PMID: 19123328
Source
Medline
License
Unknown

Abstract

GA can inhibit invasive capacity of K562 and HL-60 leukemia cells by way of suppressing the activity of gelatinase A and B. This study provides an experimental evidence for preventing extra-medullary infiltration of leukemic cells.

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