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The effect of extracorporeal electromagnetic shock waves on renal proximal tubular function.

Authors
  • Kirkali, Z
  • Kirkali, G
  • Tahiri, Y
Type
Published Article
Journal
International urology and nephrology
Publication Date
Jan 01, 1994
Volume
26
Issue
3
Pages
255–257
Identifiers
PMID: 7960534
Source
Medline
License
Unknown

Abstract

In order to investigate the effect of electromagnetic shock waves on proximal tubular renal function, we measured the urine levels of the lysosomal enzyme N-acetyl-beta-glucosaminidase (NAG) prior to, 1 hour, 1 day, and 1 week after extracorporeal electromagnetic lithotripsy (ESWL) in 50 patients with urinary stone disease. Mean NAG level which was 5.18 + 0.09 U/l prior to ESWL increased to 5.29 + 0.09 U/l in the first hour and to 10.7 + 0.19 U/l on the first day after ESWL (p < 0.001). The level returned to pre-ESWL values one week after ESWL (5.27 + 0.09 U/l). These findings show that extracorporeal electromagnetic shock waves cause significant damage to the proximal tubular epithelium of the kidney; however, these changes return to normal in the first week.

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