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Effect of eplerenone on endothelial progenitor cells and oxidative stress in ischemic hindlimb.

Authors
  • Kobayashi, Naohiko
  • Fukushima, Hiromichi
  • Takeshima, Hiroshi
  • Koguchi, Wataru
  • Mamada, Yasuko
  • Hirata, Hisato
  • Machida, Yoshifumi
  • Suzuki, Noriko
  • Yokotsuka, Fumie
  • Tabei, Kyoko
  • Kobayashi, Eri
  • Fukuda, Noboru
  • Ishimitsu, Toshihiko
Type
Published Article
Journal
American Journal of Hypertension
Publisher
Oxford University Press
Publication Date
Sep 01, 2010
Volume
23
Issue
9
Pages
1007–1013
Identifiers
DOI: 10.1038/ajh.2010.91
PMID: 20431528
Source
Medline
License
Unknown

Abstract

This study showed that eplerenone improves the proliferation and function of EPCs in rat hindlimb ischemia, suggesting that eplerenone may provide a novel and effective therapeutic strategy for the repair of cardiovascular diseases.

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