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Effect of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestine.

Authors
Type
Published Article
Journal
Lancet (London, England)
Publication Date
Volume
354
Issue
9187
Pages
1353–1354
Identifiers
PMID: 10533866
Source
Medline
License
Unknown

Abstract

Diets containing genetically modified (GM) potatoes expressing the lectin Galanthus nivalis agglutinin (GNA) had variable effects on different parts of the rat gastrointestinal tract. Some effects, such as the proliferation of the gastric mucosa, were mainly due to the expression of the GNA transgene. However, other parts of the construct or the genetic transformation (or both) could also have contributed to the overall biological effects of the GNA-GM potatoes, particularly on the small intestine and caecum.

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