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[Effect of diet macronutrients profile on leptin concentration].

Authors
  • Hermsdorff, Helen H M
  • Volp, Ana Carolina P
  • Santos, Rosana G C
  • Viana, Mirelle L
  • Bressan, Josefina
Type
Published Article
Journal
Arquivos Brasileiros de Endocrinologia & Metabologia
Publisher
SciELO
Publication Date
Oct 01, 2006
Volume
50
Issue
5
Pages
934–943
Identifiers
PMID: 17160220
Source
Medline
License
Unknown

Abstract

The aim of this study was to investigate the effect of ingesting high-sucrose (HSD) and high-lipid diets (HLD) on the concentrations of plasma glucose and leptin in lean and overweight women. Twenty healthy women were selected: 13 lean (G1) and 7 overweight (G2). The test diets HSD (23% sucrose) and HLD (45% lipid) were calculated for intake under non-restrictive conditions during 14 days. Anthropometry, body composition, plasma glucose and leptin determinations were carried out. The fasting and postprandial plasma leptin values were higher in G2 (p< 0.05), correlating positively with the anthropometry and body composition data (p< 0.05), and special positive correlation with hip circumference. Glucose and leptin concentrations did not differ between diets. Circulating glucose 30 (p< 0.01) and 60 (p< 0.05) minutes after ingestion of HSD were positively correlated with postprandial leptin concentration. The results confirm the positive association between plasma leptin concentration and body fat, specifically the subcutaneous fat tissue, and suggest that more studies are necessary to identify the modulating role of energy intake and macronutrients profile on leptin concentration.

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