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Effect of diclofenac, ketorolac, and fluorometholone on arachidonic acid metabolites following excimer laser corneal surgery.

Authors
  • Phillips, A F
  • Hayashi, S
  • Seitz, B
  • Wee, W R
  • McDonnell, P J
Type
Published Article
Journal
Archives of Ophthalmology
Publisher
American Medical Association
Publication Date
Dec 01, 1996
Volume
114
Issue
12
Pages
1495–1498
Identifiers
PMID: 8953982
Source
Medline
License
Unknown

Abstract

As a group, topical anti-inflammatory medications tend to lower prostaglandin E2 levels in rabbit corneas subjected to excimer ablation, but differ in their ability to reduce polymorphonuclear leukocyte infiltration. Further work is needed in this model to understand how these drugs alter leukocyte infiltration of the remaining stromal bed.

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